A new sesquiterpene lactone from the aerial parts of Anthemis melanolepis L

• Published in: Planta Medica
• Main Authors: Saroglou, V, Karioti, A, Skaltsa, H
• Format: Conference Proceeding
• Language: English
• Published: 04.08.2008
• ISSN: 0032-0943; 1439-0221
• DOI: 10.1055/s-0028-1084428

Continuing our research on the chemical constituents from the aerial parts of Anthemis melanolepis L., a Greek endemic species belonging to the section Cota [1], we report here the isolation and identification of a new sesquiterpene lactone. The isolation was proceeded according to the Bohlmann isolation method, slightly modified [2]. The structure of the isolated compound 1 was elucidated by spectroscopic methods, particularly high-field NMR spectroscopy ( 1 H-NMR, 1 H- 1 H COSY, NOESY, HSQC, HMBC). Compound 1, namely anthemin C, is a new naturally occurring eudesmanolide. Besides compound 1 , there were also isolated twelve known sesquiterpene lactones, one terpene, one triterpene, eight flavonoids and three phenolic acids. Aknowledgments: This project is co-financed within Op. Education by the ESF (European Social Fund) and National Resources. References: 1. Davis, P. H. (1975) Flora of Turkey and the East Aegean islands. Edinburgh. 5:174–221. 2. Bohlmann, F. et al. (1984) Phytochemistry 23:1979–88.