Secondary metabolites of Origanum dubium Boiss. from Cyprus

• Published in: Planta Medica
• Main Authors: Milošević-Ifantis, T, Pachopos, N, Niryiannaki, N, Karioti, A, Skaltsa, H
• Format: Conference Proceeding
• Language: English
• Published: 19.07.2012
• ISSN: 0032-0943; 1439-0221
• DOI: 10.1055/s-0032-1320918

Origanum dubium Boiss. (Lamiaceae) is a flavouring and medicinal herb widely used in Cyprus. Lipophilic and polar extracts of the aerial parts were investigated for their secondary metabolites. Overall, 20 constituents were isolated. The structure of the isolated compounds was elucidated by spectroscopic methods and identified as: carvacrol, carvacrol acetate, thymoquinol-2- O - β -glucopyranoside, thymoquinol-5- O - β -glucopyranoside, spathulenol, oleanolic acid, ursolic acid, arbutoside, seguinoside-B, osmantolide, p -coumaric acid, apigenin, luteolin, xanthomicrol, apigenin-7- O - β -D-glucopyranoside, 6-hydroxykaempferol 3-methylether-6- O - β -D-glucopyranoside, naringenin, eriodictyol, 12- O -hydroxyjasmonic acid, 12- O -hydroxyjasmonic acid- 12- O - β -glucopyranoside. None of them was previously reported as constituents of O. dubium Boiss., while the phenolic derivatives-hydroquinone glycosides are reported for the first time as constituents of the Lamiaceae family. Hydroquinone glycosides from O. dubium Boiss.