Brain Tumors Surgical Treatment and Pregnancy

Introduction: In 75% cases tumors are progressing in reproductive age. Placenta is a powerful hormonal body stimulating the tumors growth. Maternal fatality is 24.3%. Aim: Formulate treatment tactics. Material and Methods: 22 women (2009-2014) were surgically treated with clinical symptoms mistakenl...

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Bibliographic Details
Published inJournal of Neurological Surgery Part A: Central European Neurosurgery
Main Authors Аkshulakov, S.К., Olenbay, G.I., Ryskeldiyev, N. A., Doskaliev, A. Z., Surdin, D. A.
Format Conference Proceeding
LanguageEnglish
Published 27.05.2014
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Summary:Introduction: In 75% cases tumors are progressing in reproductive age. Placenta is a powerful hormonal body stimulating the tumors growth. Maternal fatality is 24.3%. Aim: Formulate treatment tactics. Material and Methods: 22 women (2009-2014) were surgically treated with clinical symptoms mistakenly interpreted as an early preeclampsia - headache 100% and vomiting 42%. The treatment choice agreed with neurosurgeons, anesthesiologists and obstetricians. 14 of 22 patients surgically treated in postnatal period. Delivery performed by cesarean section, 6 patients produced fetus wastage, 2 (19-20 and 25-26 weeks) with surgical treatment under fetal ultrasound and obstetricians monitoring, performed with StealthStation and Medtronik navigation systems providing us with optimal access and visualization of low-grade gliomas with no clear boundaries and difficult location. Results: Glial tumors are prevail 9 of 22 (40.9%), 4 (44.4%) have fibrillar protoplasmic astrocytoma, 3 (33.3%) anaplastic astrocytoma, 2 (22.2%) glioblastoma multiforme, 4 (18.1%) meningiomas, 1 (25%) atypical meningioma, 2 (9.0%) hemangioblastoma anaplastic, 2 (9,0%) ependymoma. After 3 months CT and MRI showed total removal 12 (54.5%) and 9 (40.9%) subtotal removal. 1 (4.54%) - verifies the histological autopsy. One fatality case among 22, rated as (4.54%). Conclusion: Surgical treatment depends on neurological condition, location of tumor and gestation and is not an absolute indication for fetus wastage.
ISSN:2193-6315
2193-6323
DOI:10.1055/s-0034-1382166