Feocromocitoma y Paraganglioma: un reto más allá de la clínica
Los feocromocitomas y paragangliomas son tumores raros que se originan en las células cromafines. Tienen un amplio espectro clínico que va desde el hallazgo incidental hasta manifestaciones por la producción exagerada de catecolaminas. El diagnóstico bioquímico se realiza mediante medición de metane...
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Published in | Revista colombiana de cancerología (1999) Vol. 25; no. 1; pp. 3 - 12 |
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Main Authors | , , |
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Abstract | Los feocromocitomas y paragangliomas son tumores raros que se originan en las células cromafines. Tienen un amplio espectro clínico que va desde el hallazgo incidental hasta manifestaciones por la producción exagerada de catecolaminas. El diagnóstico bioquímico se realiza mediante medición de metanefrinas libres en plasma. El tratamiento ideal es la escisión quirúrgica completa previo bloqueo de receptores α y β adrenérgicos. En caso de enfermedad metastásica, las opciones de tratamiento sistémico actuales son limitadas y con escasa tasa de respuesta. Está en investigación el uso de antiangiogénicos. |
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AbstractList | Resumen Los feocromocitomas y paragangliomas son tumores raros que se originan en las células cromafines. Tienen un amplio espectro clínico que va desde el hallazgo incidental hasta manifestaciones por la producción exagerada de catecolaminas. El diagnóstico bioquímico se realiza mediante medición de metanefrinas libres en plasma. El tratamiento ideal es la escisión quirúrgica completa previo bloqueo de receptores a y 6 adrenérgicos. En caso de enfermedad metastásica, las opciones de tratamiento sistêmico actuales son limitadas y con escasa tasa de respuesta. Está en investigación el uso de antiangiogénicos. Los feocromocitomas y paragangliomas son tumores raros que se originan en las células cromafines. Tienen un amplio espectro clínico que va desde el hallazgo incidental hasta manifestaciones por la producción exagerada de catecolaminas. El diagnóstico bioquímico se realiza mediante medición de metanefrinas libres en plasma. El tratamiento ideal es la escisión quirúrgica completa previo bloqueo de receptores α y β adrenérgicos. En caso de enfermedad metastásica, las opciones de tratamiento sistémico actuales son limitadas y con escasa tasa de respuesta. Está en investigación el uso de antiangiogénicos. |
Author | Amado Garzón, Sandra Molina Pimienta, Luisana Salgado Sánchez, Juan Camilo |
AuthorAffiliation | Hospital Universitario San Ignacio Pontificia Universidad Javeriana |
AuthorAffiliation_xml | – name: Hospital Universitario San Ignacio – name: Pontificia Universidad Javeriana |
Author_xml | – sequence: 1 givenname: Luisana orcidid: 0000-0001-5505-9710 surname: Molina Pimienta fullname: Molina Pimienta, Luisana – sequence: 2 givenname: Juan Camilo orcidid: 0000-0002-5956-4834 surname: Salgado Sánchez fullname: Salgado Sánchez, Juan Camilo – sequence: 3 givenname: Sandra orcidid: 0000-0002-7756-1805 surname: Amado Garzón fullname: Amado Garzón, Sandra |
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DocumentTitleAlternate | Pheochromocytoma and Paraganglioma: a Challenge beyond the Clinic |
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Keywords | Metanephrine Pheochromocytoma Metanefrina Surgery Quimioterapia Drug Therapy Feocromocitoma Paraganglioma Cirugía |
Language | English Portuguese |
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Snippet | Los feocromocitomas y paragangliomas son tumores raros que se originan en las células cromafines. Tienen un amplio espectro clínico que va desde el hallazgo... Resumen Los feocromocitomas y paragangliomas son tumores raros que se originan en las células cromafines. Tienen un amplio espectro clínico que va desde el... |
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Title | Feocromocitoma y Paraganglioma: un reto más allá de la clínica |
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