Feocromocitoma y Paraganglioma: un reto más allá de la clínica

Los feocromocitomas y paragangliomas son tumores raros que se originan en las células cromafines. Tienen un amplio espectro clínico que va desde el hallazgo incidental hasta manifestaciones por la producción exagerada de catecolaminas. El diagnóstico bioquímico se realiza mediante medición de metane...

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Published inRevista colombiana de cancerología (1999) Vol. 25; no. 1; pp. 3 - 12
Main Authors Molina Pimienta, Luisana, Salgado Sánchez, Juan Camilo, Amado Garzón, Sandra
Format Journal Article
LanguageEnglish
Portuguese
Published Instituto Nacional de Cancerología E.S.E 12.03.2021
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Abstract Los feocromocitomas y paragangliomas son tumores raros que se originan en las células cromafines. Tienen un amplio espectro clínico que va desde el hallazgo incidental hasta manifestaciones por la producción exagerada de catecolaminas. El diagnóstico bioquímico se realiza mediante medición de metanefrinas libres en plasma. El tratamiento ideal es la escisión quirúrgica completa previo bloqueo de receptores α y β adrenérgicos. En caso de enfermedad metastásica, las opciones de tratamiento sistémico actuales son limitadas y con escasa tasa de respuesta. Está en investigación el uso de antiangiogénicos.
AbstractList Resumen Los feocromocitomas y paragangliomas son tumores raros que se originan en las células cromafines. Tienen un amplio espectro clínico que va desde el hallazgo incidental hasta manifestaciones por la producción exagerada de catecolaminas. El diagnóstico bioquímico se realiza mediante medición de metanefrinas libres en plasma. El tratamiento ideal es la escisión quirúrgica completa previo bloqueo de receptores a y 6 adrenérgicos. En caso de enfermedad metastásica, las opciones de tratamiento sistêmico actuales son limitadas y con escasa tasa de respuesta. Está en investigación el uso de antiangiogénicos.
Los feocromocitomas y paragangliomas son tumores raros que se originan en las células cromafines. Tienen un amplio espectro clínico que va desde el hallazgo incidental hasta manifestaciones por la producción exagerada de catecolaminas. El diagnóstico bioquímico se realiza mediante medición de metanefrinas libres en plasma. El tratamiento ideal es la escisión quirúrgica completa previo bloqueo de receptores α y β adrenérgicos. En caso de enfermedad metastásica, las opciones de tratamiento sistémico actuales son limitadas y con escasa tasa de respuesta. Está en investigación el uso de antiangiogénicos.
Author Amado Garzón, Sandra
Molina Pimienta, Luisana
Salgado Sánchez, Juan Camilo
AuthorAffiliation Hospital Universitario San Ignacio
Pontificia Universidad Javeriana
AuthorAffiliation_xml – name: Hospital Universitario San Ignacio
– name: Pontificia Universidad Javeriana
Author_xml – sequence: 1
  givenname: Luisana
  orcidid: 0000-0001-5505-9710
  surname: Molina Pimienta
  fullname: Molina Pimienta, Luisana
– sequence: 2
  givenname: Juan Camilo
  orcidid: 0000-0002-5956-4834
  surname: Salgado Sánchez
  fullname: Salgado Sánchez, Juan Camilo
– sequence: 3
  givenname: Sandra
  orcidid: 0000-0002-7756-1805
  surname: Amado Garzón
  fullname: Amado Garzón, Sandra
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DocumentTitleAlternate Pheochromocytoma and Paraganglioma: a Challenge beyond the Clinic
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Issue 1
Keywords Metanephrine
Pheochromocytoma
Metanefrina
Surgery
Quimioterapia
Drug Therapy
Feocromocitoma
Paraganglioma
Cirugía
Language English
Portuguese
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Snippet Los feocromocitomas y paragangliomas son tumores raros que se originan en las células cromafines. Tienen un amplio espectro clínico que va desde el hallazgo...
Resumen Los feocromocitomas y paragangliomas son tumores raros que se originan en las células cromafines. Tienen un amplio espectro clínico que va desde el...
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SubjectTerms MEDICINE, GENERAL & INTERNAL
Title Feocromocitoma y Paraganglioma: un reto más allá de la clínica
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