ZrCl 4 -promoted facile synthesis of indole derivatives

Zirconium( iv ) chloride effectively activates nitrogen (N 2 ) extrusion from aryl azidoacrylates followed by annulation to provide the desired indole products in moderate to good yields. The reaction proceeds at low temperature and in short reaction time and is applicable to a variety of substrates...

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Bibliographic Details
Published inRSC advances Vol. 4; no. 38; pp. 20048 - 20052
Main Authors Tummatorn, J., Gleeson, M. P., Krajangsri, S., Thongsornkleeb, C., Ruchirawat, S.
Format Journal Article
LanguageEnglish
Published 2014
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Summary:Zirconium( iv ) chloride effectively activates nitrogen (N 2 ) extrusion from aryl azidoacrylates followed by annulation to provide the desired indole products in moderate to good yields. The reaction proceeds at low temperature and in short reaction time and is applicable to a variety of substrates.
ISSN:2046-2069
2046-2069
DOI:10.1039/C4RA02158D