malERA: An updated research agenda for health systems and policy research in malaria elimination and eradication

• Published in: PLoS medicine Vol. 14; no. 11; p. e1002454
• Main Authors: Panel on Health Systems, Research, Policy
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 30.11.2017; Public Library of Science (PLoS)
• Subjects: Analysis; Animals; Biomedical Research - methods; Biomedical Research - trends; Collection Review; Delivery of Health Care - methods; Delivery of Health Care - trends; Disease Eradication - methods; Disease Eradication - trends; Global health; Health policy; Health Policy - trends; Humans; Malaria; Malaria - epidemiology; Malaria - prevention & control; Medicine and Health Sciences; Policy research; Prevention; Public health; R&D; Research & development; Researchers; Science Policy; Social Sciences; Support systems; System effectiveness; Vector-borne diseases; United States
• ISSN: 1549-1676; 1549-1277; 1549-1676
• DOI: 10.1371/journal.pmed.1002454

Health systems underpin disease elimination and eradication programmes. In an elimination and eradication context, innovative research approaches are needed across health systems to assess readiness for programme reorientation, mitigate any decreases in effectiveness of interventions ('effectiveness decay'), and respond to dynamic and changing needs. The malaria eradication research agenda (malERA) Refresh consultative process for the Panel on Health Systems and Policy Research identifies opportunities to build health systems evidence and the tools needed to eliminate malaria from different zones, countries, and regions and to eradicate it globally. The research questions are organised as a portfolio that global health practitioners, researchers, and funders can identify with and support. This supports the promotion of an actionable and more cohesive approach to building the evidence base for scaled-up implementation of findings. Gaps and opportunities discussed in the paper include delivery strategies to meet the changing dynamics of needs of individuals, environments, and malaria programme successes; mechanisms and approaches to best support accelerated policy and financial responsiveness at national and global level to ensure timely response to evidence and needs, including in crisis situations; and systems' readiness tools and decision-support systems.