Sexual Dysfunction among Females Receiving Psychotropic Medication: A Hospital-based Cross-sectional Study

• Published in: Indian journal of psychological medicine Vol. 38; no. 5; pp. 447 - 454
• Main Authors: Shetageri, Veda N., Bhogale, Govind S., Patil, N. M., Nayak, R. B., Chate, S. S.
• Format: Journal Article
• Language: English
• Published: New Delhi, India SAGE Publications 01.09.2016; Wolters Kluwer India Pvt. Ltd; Sage Publications Ltd. (UK); Sage Publications, New Delhi India; Medknow Publications & Media Pvt Ltd; SAGE Publishing
• Subjects: Antipsychotic agents; Clinical global impression; Drug therapy; Drugs; female sexual dysfunction; female sexual function index; Medical research; Original; psychotropics; Sexual disorders; sexual dysfunction; side effects; Tricyclic antidepressants; India; side effects; female sexual dysfunction; female sexual function index; sexual dysfunction; psychotropics; Clinical global impression
• ISSN: 0253-7176; 0975-1564
• DOI: 10.4103/0253-7176.191379

Background: Sexual dysfunction (SD) is a known adverse effect of psychotropic medications. Even though sexual difficulties are common among women; very few studies have been carried out in India. Objective: To study the prevalence and nature of SD among females receiving psychotropic medications and to compare the SD among female patients receiving antipsychotics and antidepressants. Materials and Methods: Female investigator conducted a hospital-based cross-sectional study on female patients visiting the psychiatry outpatient department. Patients meeting inclusion criteria were assessed for SD disorder as per Diagnostic and Statistical Manual of Mental Disorders 4th Edition Text Revision. SD severity was measured using Female Sexual Function Index (FSFI) scale. Results: The prevalence of SD in this study was 68.32%. There was more than one SD in 48 (47.52%). FSFI score was significantly low in patients with SD as compared to patients not having SD (P = 0.001). SD was more common in patients who were on combination of antidepressants and benzodiazepines than antidepressant alone or antipsychotic alone. Conclusion: SD was prevalent in more than 50% of female patients on psychotropic drugs. Number of patients on individual psychotropic drugs was so small that a definite conclusion could not be drawn. Study emphasizes the need to carry out similar study on larger number of patients to get better insight into this problem.