Monitoring of osteoporosis among geriatric population in the primary care service
Introduction. Osteoporosis is a chronic, progressive bone disease which leads to a reduction in bone mineral density and disruption of bone micro-architecture. Patients with osteoporosis have an increased risk of fractures caused by ?small trauma? - stresses which would not normally cause fracture i...
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| Published in | Medicinski pregled Vol. 67; no. suppl. 2; pp. 52 - 56 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
2014
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| Online Access | Get full text |
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| Summary: | Introduction. Osteoporosis is a chronic, progressive bone disease which leads
to a reduction in bone mineral density and disruption of bone
micro-architecture. Patients with osteoporosis have an increased risk of
fractures caused by ?small trauma? - stresses which would not normally cause
fracture in a non-osteoporotic individual. This study was aimed at
determining the incidence of osteoporosis in geriatric population, crucial
demographic parameters (gender and age structure) in patients, presence of
comorbidities, and the most common drug choice in treatment of osteoporosis.
Material and Methods. A retrospective study was conducted in the period from
August 1st, 2012 to May 12th, 2014 and it included 526 patients over 65 years
of age who were diagnosed to have osteoporosis based on clinical findings
(presence/absence of pathological fractures), laboratory tests and
osteodensitometry. Data were analyzed by using standard statistical methods
and statistical significance was assessed by x2 and t - test. Results. The
most affected patients were women (91%). The incidence of pathological
fractures was 31.80%. The presence of two or more fractures caused by a
?small trauma? was determined in 13.6%. Cardiovascular comorbidities
dominated in 72.70% of cases. The most common therapeutic choice was the
bisphosphonates, being administered in 77% along with the simultaneous use of
vitamin D analogs - alfacalciferol (13.6%), cholecalciferol (40.9%), calcium
carbonate + cholecalciferol (22.7%). Conclusion. Osteoporosis shows
predominance in females aged 65-70 years. Comorbidities do not increase the
risk of disease but significantly reduce the quality of life in patients.
Bisphosphonates are the most common drug choice with the simultaneous use of
calcium and vitamin D analogs.
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| ISSN: | 0025-8105 1820-7383 |
| DOI: | 10.2298/MPNS14S2052S |