Functional subdivision of group-ICA results of fMRI data collected during cinema viewing

• Published in: PloS one Vol. 7; no. 7; p. e42000
• Main Authors: Pamilo, Siina, Malinen, Sanna, Hlushchuk, Yevhen, Seppä, Mika, Tikka, Pia, Hari, Riitta
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 30.07.2012; Public Library of Science (PLoS)
• Subjects: Adult; Attention; Biology; Brain; Brain - physiology; Brain mapping; Brain research; Cognition & reasoning; Decomposition; Drama; Emotions; Engineering; Functional magnetic resonance imaging; Humans; Independent component analysis; Laboratories; Magnetic resonance; Magnetic Resonance Imaging; Medicine; Networks; Neuroimaging; NMR; Nuclear magnetic resonance; Reproducibility of Results; Science; Sensorimotor system; Social and Behavioral Sciences; Studies; Trends; Viewing; Finland
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0042000

Independent component analysis (ICA) can unravel functional brain networks from functional magnetic resonance imaging (fMRI) data. The number of the estimated components affects both the spatial pattern of the identified networks and their time-course estimates. Here group-ICA was applied at four dimensionalities (10, 20, 40, and 58 components) to fMRI data collected from 15 subjects who viewed a 15-min silent film ("At land" by Maya Deren). We focused on the dorsal attention network, the default-mode network, and the sensorimotor network. The lowest dimensionalities demonstrated most prominent activity within the dorsal attention network, combined with the visual areas, and in the default-mode network; the sensorimotor network only appeared with ICA comprising at least 20 components. The results suggest that even very low-dimensional ICA can unravel the most prominent functionally-connected brain networks. However, increasing the number of components gives a more detailed picture and functionally feasible subdivision of the major networks. These results improve our understanding of the hierarchical subdivision of brain networks during viewing of a movie that provides continuous stimulation embedded in an attention-directing narrative.