Relationship between anthropometric parameters and open angle glaucoma: The Korea National Health and Nutrition Examination Survey

• Published in: PloS one Vol. 12; no. 5; p. e0176894
• Main Authors: Lee, Jae Yeun, Kim, Tae-Woo, Kim, Hyun Tae, Lee, Mi Yeon, Min, Hye Won, Won, Yu Sam, Kwon, Hyun Seok, Park, Ki Ho, Kim, Joon Mo
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 08.05.2017; Public Library of Science (PLoS)
• Subjects: Adult; Age; Alcoholic beverages; Analysis; Anthropometry; Biology and Life Sciences; Body composition; Body fat; Body mass; Body mass index; Body measurements; Bone mass; Cardiovascular disease; Care and treatment; Data processing; Dementia; Diabetes mellitus; Diabetic retinopathy; Diagnosis; Epidemiology; Exercise; Family medical history; Female; Females; Glaucoma; Glaucoma, Open-Angle - pathology; Hospitals; Humans; Hypertension; Intraocular pressure; Lean body mass; Male; Males; Medicine; Medicine and Health Sciences; Metabolic syndrome; Middle Aged; Nutrition; Nutrition Surveys; Obesity; Ophthalmology; Physical fitness; Population; Population studies; Probabilistic methods; Quartiles; Republic of Korea; Review boards; Sarcopenia; Skeletal muscle; Smoking; Studies; South Korea
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0176894

To evaluate the relationships between open-angle glaucoma (OAG) and various anthropometric measurements. Korea National Health and Nutrition Examination Survey (KNHANES), a population-based cross-sectional study using a complex, stratified, multistage, probability-cluster survey. A total of 5,255 participants including 247 glaucoma patients, aged ≥ 19 years were included from the KNHANES V database. Glaucoma diagnosis was based on International Society of Geographical and Epidemiological Ophthalmology criteria. Various anthropometric data regarding obesity were analyzed including body mass index (BMI), total body fat mass, total body muscle mass (lean body mass, non-bone lean body mass, and appendicular skeletal muscle (ASM) mass), and waist circumference (WC). The differences in OAG prevalence with respect to anthropometric parameter quartiles were examined. In males, the multivariate general linear model adjusted for age, alcohol, smoking, exercise, systemic hypertension, diabetes, and intraocular pressure (IOP) showed the quartiles for the anthropometric parameters BMI, fat mass/weight ratio and fat mass/muscle mass ratio were negatively associated with OAG. However, muscle mass parameter/BMI ratio was significantly positively associated with OAG (P for trend<0.05). In females, height and fat mass/BMI showed a significant relationship with the risk of OAG. (P value<0.05). In the present study, high fat mass was associated with low OAG risk. Body composition seemed to affect the prevalence of OAG, but further evaluation is needed.