Evaluation of 3-tier and 5-tier FHR pattern classifications using umbilical blood pH and base excess at delivery

• Published in: PloS one Vol. 15; no. 2; p. e0228630
• Main Authors: Kikuchi, Hitomi, Noda, Shunichi, Katsuragi, Shinji, Ikeda, Tomoaki, Horio, Hiroyuki
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 06.02.2020; Public Library of Science (PLoS)
• Subjects: Adult; Agreements; Analysis; Biology and Life Sciences; Blood; Blood Gas Analysis; Classification; Classification systems; Delivery (Childbirth); Delivery, Obstetric; Female; Fetal Blood; Fetal Monitoring - methods; Fetuses; Gynecology; Heart rate; Heart Rate, Fetal; Humans; Hydrogen-Ion Concentration; Informatics; Labor, Obstetric; Medicine and Health Sciences; Obstetrics; Pattern classification; People and Places; pH effects; Physical Sciences; Pregnancy; Research and Analysis Methods; Standard deviation; Time; Time Factors; Time series; Umbilical Arteries; Vagina; Veins & arteries; United Kingdom; Canada; United Kingdom > UK; United States > US; Japan
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0228630

The relevance between time-series fetal heart rate (FHR) pattern changes during labor and outcomes such as arterial blood gas data at delivery has not been studied. Using 3-tier and 5-tier classification systems, we studied the relationship between time-series FHR pattern changes before delivery and umbilical artery blood gas data at delivery. The subjects were 1,909 low-risk women with vaginal delivery (age: 29.1 ± 4.4 years, parity: 1.7 ± 0.8). FHR patterns were classified by a skilled obstetrician based on each 10 min-segment of the last 60 min before delivery from continuous CTG records in an obstetric clinic. The relationship between each 10 min-segment FHR pattern classification from 60 minutes before delivery and umbilical artery blood pH and base excess (BE) values at delivery changed with time. In the 3-tier classification, mean pH of Category I group in each 10 min-segment was significantly higher than that of Category II group. For Category I groups in each 10-minute segment, its number decreased and its average pH increased as the delivery time approached. In the 5-tier classification, there was the same tendency. About each level group in 10 min-segment, the higher the level, the lower the blood gas values, and mean pH of higher level groups decreased as the delivery time approached. The relationship between classifications and outcomes was clear at any time from 60 min before delivery in 3- and 5-tier classifications, and the 5-tier classification was more relevant.