Serum Cys C Assessment in Healthy Indian Population and Chronic Kidney Failure Individuals – A Case Control Study

• Published in: RGUHS Journal of Allied Health Sciences Vol. 1; no. 1
• Main Authors: S, Sagar, Salman, Mr, Joy, Remya, Babu SV, Suresh
• Format: Journal Article
• Language: English
• Published: 2021
• ISSN: 2583-3782; 2583-3782
• DOI: 10.26463/rjahs.1_1_7

Background Serum Cys C has been acknowledged as a simple and reliable biomarker for assessing renal function in research studies. Evolving evidence show its efficacy in improving the diagnostic approach when included in routine clinical practice. Objectives The study intended to evaluate and compare serum Cys C sCys C levels in healthy individuals with chronic kidney diseases.Materials and Methods A case control observational study was conducted at Padmashree Diagnostic Centre Vijayanagar Bengaluru. The sCys C test was assayed by latex enhanced immunoturbidometric method.Result Serum Cys C levels assessed in normal subjects was in the range of 1.03 plusmn 0.11 mgL comparable to the available reference interval for normal healthy population while sCys C values were between 3.55 and 4.71mgL with mean value of 4.3 mgL SDplusmn0.34 in chronic kidney patients. The results displayed significant increase in the values of serum Cys C in chronic kidney disease patients.Conclusion To conclude sCys C is a convenient diagnostic instrument for calculating the functional ability of the kidneys. Furthermore serum Cys C can be included in routine tests for clinical decision making and in the health care package for renal function.