Evaluation of the antifungal efficacy of different concentrations of Curcuma longa on Candida albicans: an in vitro study

Introduction Fungal infections have increased significantly contributing to the cause of morbidity and mortality. The increase in antimicrobial resistance and number of patients at risk in conjunction with the restricted number of commercially available antifungal drugs that still present many side...

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Bibliographic Details
Published inRGUHS Journal of Medical Sciences Vol. 10; no. 3
Main Authors Murugesh, Jeevitha, G Annigeri, Rajeshwari, Kallapur, Mangala, Jyothi, Mangal, J Smitha B Gujjar, K
Format Journal Article
LanguageEnglish
Published 2020
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Summary:Introduction Fungal infections have increased significantly contributing to the cause of morbidity and mortality. The increase in antimicrobial resistance and number of patients at risk in conjunction with the restricted number of commercially available antifungal drugs that still present many side effects are the cause for this problem. These limitations emphasize the need to develop new and more effective antifungal agents.Materials and Methods The present study was undertaken to investigate the possible antifungal action of the alcoholic extract of Curcuma longa in different concentrations on four dilutions of candida albicans 110 120 140 180 and to determine its Minimum Inhibitory Concentration MIC using Seaboardrsquos agar medium.Results There was complete inhibition of the growth of all four dilutions of Candida at a concentration of 800 microl which is considered as the Minimum Inhibitory Concentration MIC of alcoholic extract of turmeric on Candida albicans.Conclusion The study indicates a potent antifungal action of C. longa against Candida albicans.
ISSN:2231-1947
2581-7248
DOI:10.26463/rjms.10_3_6