Cerebral Syphilitic Gumma in Immunocompetent Man, Japan

• Published in: Emerging Infectious Diseases Vol. 24; no. 2; pp. 395 - 396
• Main Authors: Kodama, Tatsuya, Sato, Hidenori, Osa, Morichika, Fujikura, Yuji, Kawana, Akihiko
• Format: Journal Article
• Language: English
• Published: United States Centers for Disease Control and Prevention (CDC) 01.02.2018; U.S. National Center for Infectious Diseases; Centers for Disease Control and Prevention
• Subjects: Adult; Anti-Bacterial Agents - therapeutic use; bacteria; Ceftriaxone - therapeutic use; Cerebral Syphilitic Gumma in Immunocompetent Man, Japan; Health aspects; Humans; Immunocompromised Host; Infectious and parasitic diseases; Japan; Japan - epidemiology; Male; Medical schools; Medicine; neurosyphilis; Neurosyphilis - diagnosis; Neurosyphilis - diagnostic imaging; Neurosyphilis - drug therapy; Neurosyphilis - epidemiology; R; RC109-216; Research Letter; Sex oriented businesses; sexually transmitted infections; Syphilis; syphilitic gumma; Japan; syphilitic gumma; bacteria; sexually transmitted infections; Japan; syphilis; neurosyphilis; cerebral syphilitic gumma
• ISSN: 1080-6040; 1080-6059; 1080-6059
• DOI: 10.3201/eid2402.171444

Although cerebral syphilitic gummas are generally considered to be rare manifestations of tertiary syphilis, many reports exist of early cerebral syphilitic gumma. Our finding of cerebral syphilitic gumma in an HIV-negative man within 5 months after syphilis infection suggests that this condition should be considered in syphilis patients who have neurologic symptoms.