Sheep Red Blood Cell Instillation at Palatine Tonsil Effectively Induces Specific IgA Class Antibody in Saliva in Rabbits

• Published in: MICROBIOLOGY and IMMUNOLOGY Vol. 39; no. 5; pp. 351 - 359
• Main Authors: Fukuizumi, Takaki, Inoue, Hiromasa, Anzai, Yuichi, Tsujisawa, Toshiyuki, Uchiyama, Choji
• Format: Journal Article
• Language: English
• Published: Tokyo Blackwell Publishing Ltd 01.01.1995; Center For Academic Publications Japan; Center for Academic Publications Japan
• Subjects: Administration, Intranasal; Analysis of the immune response. Humoral and cellular immunity; Animals; Antibody production; Antibody-Producing Cells - immunology; Antigens - administration & dosage; Biological and medical sciences; Chemotaxis, Leukocyte; Erythrocytes - immunology; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Immunobiology; Immunoglobulin A - biosynthesis; Lymphocyte Count; Lymphoid Tissue - immunology; Mucosal immunity; Organ Specificity; Palatine tonsil; Palatine Tonsil - immunology; Rabbits; Saliva; Saliva - immunology; Salivary Proteins and Peptides - immunology; Secretory IgA; Sheep - blood; Stomach; Oral cavity; Vertebrata; IgA; Local immunity; Mammalia; Immune response; Mouse; Antibody; Rodentia; Saliva; Humoral immunity

We have shown that the palatine tonsil effectively incorporates exogenous foreign substances instilled at its surface. It is not clear whether antigen-specific IgA can be induced by the instillation. Sheep red blood cells (SRBC) were instilled at the palatine tonsil every three days as the antigen,...