Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 by WHO-Recommended Hand Rub Formulations and Alcohols

Infection control instructions call for use of alcohol-based hand rub solutions to inactivate severe acute respiratory syndrome coronavirus 2. We determined the virucidal activity of World Health Organization-recommended hand rub formulations, at full strength and multiple dilutions, and of the acti...

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Bibliographic Details
Published inEmerging infectious diseases Vol. 26; no. 7; pp. 1592 - 1595
Main Authors Kratzel, Annika, Todt, Daniel, V'kovski, Philip, Steiner, Silvio, Gultom, Mitra, Thao, Tran Thi Nhu, Ebert, Nadine, Holwerda, Melle, Steinmann, Jörg, Niemeyer, Daniela, Dijkman, Ronald, Kampf, Günter, Drosten, Christian, Steinmann, Eike, Thiel, Volker, Pfaender, Stephanie
Format Journal Article
LanguageEnglish
Published United States U.S. National Center for Infectious Diseases 01.07.2020
Centers for Disease Control and Prevention
Subjects
2-propanol
Alcohol
Alcohols
Alcohols - pharmacology
Betacoronavirus - drug effects
coronavirus disease
Coronavirus Infections - prevention & control
Coronaviruses
COVID-19
Cytotoxicity
Disease transmission
Disinfectants - pharmacology
Disinfection & disinfectants
Dispatch
Epidemics
Ethanol
Expedited
Glycerol
Hand Disinfection - methods
hand sanitizer
Health aspects
Humans
Hydrogen peroxide
Hygiene
Inactivation of SARS-CoV-2 by WHO-Recommended Hand Rub Formulations and Alcohols
Middle East respiratory syndrome
Pandemics - prevention & control
Patient safety
Pneumonia, Viral - prevention & control
Regression analysis
Respiratory diseases
respiratory infections
SARS-CoV-2
Severe acute respiratory syndrome
Severe acute respiratory syndrome coronavirus 2
Virology
Virus Inactivation
Viruses
World Health Organization
Switzerland
viruses
2-propanol
World Health Organization
SARS
coronavirus
zoonoses
ethanol
hand sanitizer
respiratory infections
COVID-19
SARS-CoV-2
severe acute respiratory syndrome coronavirus 2
2019 novel coronavirus disease
coronavirus disease
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Summary:Infection control instructions call for use of alcohol-based hand rub solutions to inactivate severe acute respiratory syndrome coronavirus 2. We determined the virucidal activity of World Health Organization-recommended hand rub formulations, at full strength and multiple dilutions, and of the active ingredients. All disinfectants demonstrated efficient virus inactivation.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1080-6040
1080-6059
DOI:10.3201/eid2607.200915