Protective Immunity and Persistent Lung Sequelae in Domestic Cats after SARS-CoV-2 Infection

• Published in: Emerging infectious diseases Vol. 27; no. 2; pp. 660 - 663
• Main Authors: Chiba, Shiho, Halfmann, Peter J., Hatta, Masato, Maemura, Tadashi, Fan, Shufang, Armbrust, Tammy, Swartley, Olivia M., Crawford, LaTasha K., Kawaoka, Yoshihiro
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01.02.2021; Centers for Disease Control and Prevention
• Subjects: Animal euthanasia; Animals; Care and treatment; Cat Diseases - immunology; Cat Diseases - virology; Cats; coronavirus disease; Coronaviruses; COVID-19; COVID-19 - immunology; COVID-19 - veterinary; COVID-19 - virology; Development and progression; Disease transmission; Immune response; Infections; Infectious diseases; Influenza; Large intestine; Lung - immunology; Lung - virology; Lungs; Physiological aspects; Protective Immunity and Persistent Lung Sequelae in Domestic Cats after SARS-CoV-2 Infection; R&D; Research & development; Research Letter; Respiratory diseases; respiratory infections; Respiratory tract diseases; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Virus Replication - immunology; Viruses; United States; Japan; COVID-19; SARS-CoV-2; reinfection; viruses; cats; severe acute respiratory syndrome coronavirus 2; lung sequelae; zoonoses; coronavirus disease; respiratory infections; protective immunity
• ISSN: 1080-6040; 1080-6059; 1080-6059
• DOI: 10.3201/eid2702.203884

Severe acute respiratory syndrome coronavirus 2 readily transmits between domestic cats. We found that domestic cats that recover from an initial infection might be protected from reinfection. However, we found long-term persistence of inflammation and other lung lesions after infection, despite a lack of clinical symptoms and limited viral replication in the lungs.