Management of insecticide resistance in the major Aedes vectors of arboviruses: Advances and challenges

• Published in: PLOS Neglected Tropical Diseases Vol. 13; no. 10; p. e0007615
• Main Authors: Dusfour, Isabelle, Vontas, John, David, Jean-Philippe, Weetman, David, Fonseca, Dina M., Corbel, Vincent, Raghavendra, Kamaraju, Coulibaly, Mamadou B., Martins, Ademir J., Kasai, Shinji, Chandre, Fabrice
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science (PLoS) 10.10.2019; Public Library of Science
• Subjects: [SDV]Life Sciences [q-bio]; Adulticides; Aedes; Aedes - virology; Aedes aegypti; Aedes albopictus; Agricultural management; Agricultural pests; Agrochemicals; Animals; Aquatic insects; Arbovirus Infections; Arbovirus Infections - transmission; Arboviruses; Arboviruses - physiology; Arctic medicine. Tropical medicine; Asian tiger mosquito; Bioassays; Biological assays; Biology; Biology and Life Sciences; Chikungunya Fever; Chikungunya Fever - transmission; Control programs; Dengue; Dengue - transmission; Dengue fever; Development and progression; Disease; Disease control; Epidemics; Evolution; Fever; Health risks; Human diseases; Humans; Insect Control; Insecticide Resistance; Insecticides; Insecticides - pharmacology; Laboratories; Landscape; Life Sciences; Malaria; Medicine and Health Sciences; Mortality; Mosquito Vectors; Mosquito Vectors - virology; Mosquitoes; Mutation; Pesticide resistance; Pesticides; Pests; Public aspects of medicine; Public Health; Public health movements; qw_160; qx_525; RA1-1270; RC955-962; Review; Strategic planning (Business); Systematic review; Transmission; Tropical diseases; Vector-borne diseases; Vectors; Viral diseases; wa_240; Yellow Fever; Yellow Fever - transmission; Zika Virus; Zika Virus Infection; Zika Virus Infection - transmission; Brazil; Greece; Martinique; French Guiana; France
• ISSN: 1935-2735; 1935-2727; 1935-2735
• DOI: 10.1371/journal.pntd.0007615

The landscape of mosquito-borne disease risk has changed dramatically in recent decades, due to the emergence and reemergence of urban transmission cycles driven by invasive Aedes aegypti and Ae. albopictus. Insecticide resistance is already widespread in the yellow fever mosquito, Ae. Aegypti; is emerging in the Asian tiger mosquito Ae. Albopictus; and is now threatening the global fight against human arboviral diseases such as dengue, yellow fever, chikungunya, and Zika. Because the panel of insecticides available for public health is limited, it is of primary importance to preserve the efficacy of existing and upcoming active ingredients. Timely implementation of insecticide resistance management (IRM) is crucial to maintain the arsenal of effective public health insecticides and sustain arbovirus vector control. This Review is one of a series being generated by the Worldwide Insecticide resistance Network (WIN) and aims at defining the principles and concepts underlying IRM, identifying the main factors affecting the evolution of resistance, and evaluating the value of existing tools for resistance monitoring. Based on the lessons taken from resistance strategies used for other vector species and agricultural pests, we propose a framework for the implementation of IRM strategies for Aedes mosquito vectors. Although IRM should be a fixture of all vector control programs, it is currently often absent from the strategic plans to control mosquito-borne diseases, especially arboviruses. Experiences from other public health disease vectors and agricultural pests underscore the need for urgent action in implementing IRM for invasive Aedes mosquitoes. Based on a plan developed for malaria vectors, here we propose some key activities to establish a global plan for IRM in Aedes spp.