Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1 H -indol-5-yl)-7 H -pyrrolo[2,3- d ]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)
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Published in | Journal of medicinal chemistry Vol. 55; no. 16; pp. 7193 - 7207 |
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Main Authors | , , , , , , , , , , , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
23.08.2012
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Online Access | Get full text |
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ISSN: | 0022-2623 1520-4804 |
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DOI: | 10.1021/jm300713s |