Assessing Multi-drug resistant Methicillin-Resistant Coagulase-Negative Staphylococci: Comparative Study in the Tertiary Healthcare Settings and Urban Built Environments of Vidarbha Maharashtra, India

The global challenge of antibiotic resistance is particularly pronounced in India, where hospital and urban built environments (UBE) serve as prominent reservoirs, amplifying the risk of rapid dissemination because of high population growth and inadequate surveillance. With the uncontrolled use of a...

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Bibliographic Details
Published inResearch journal of pharmacy and technology Vol. 17; no. 5; pp. 2193 - 2200
Main Authors Keshri, Anushri, Gore, Dilip G., Kolla, Varaprasad
Format Journal Article
LanguageEnglish
Published Raipur A&V Publications 15.05.2024
Subjects
Antibiotics
Antimicrobial agents
Bacteria
Disease control
Drug resistance
Health facilities
Hospitals
Investigations
Multidrug resistant organisms
Nosocomial infections
Pathogens
Public health
Staphylococcus infections
Statistical analysis
Surveillance
India
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Summary:The global challenge of antibiotic resistance is particularly pronounced in India, where hospital and urban built environments (UBE) serve as prominent reservoirs, amplifying the risk of rapid dissemination because of high population growth and inadequate surveillance. With the uncontrolled use of antibiotics and by natural genetic makeup, the resistance in staphylococci species is on the rise. In this study medical hub region Vidarbha, Maharashtra, India investigated for a resistance profile of coagulase-negative staphylococci (CoNS) once identified by a VITEK 2 and coagulase test. The antibiotic profiling was carried out by the Kirby Bauer disk diffusion method and the % resistance was calculated by statistical analysis to record significance change (P<0.05). According to the results UBE and hospital setting are positive for CoNS and prominently deducted as S. cohnii, S. haemolyticus, S. saprophyticus, S. warneri, and S. aureus. The CoNS species were found to be resistant to many antibiotics but sensitive to few, although the statistical difference was found to be non-significant (P>0.05). A study also highlighted that CoNS species in hospital environments were found to be more resistant towards the range of antibiotics compared to UBE isolates in Vidarbha. In conclusion, it has been put forward that five species of staphylococci are dominating in Vidarbha, and all of them are acquired with drug resistance which demands close surveillance in the coming time to reduce the spread of pathogens.
ISSN:0974-3618
0974-360X
0974-306X
DOI:10.52711/0974-360X.2024.00345