Guidelines for Intravenous Thrombolysis (Recombinant Tissue-type Plasminogen Activator), the Third Edition, March 2019: A Guideline from the Japan Stroke Society

• Published in: Neurologia medico-chirurgica Vol. 59; no. 12; pp. 449 - 491
• Main Authors: SHIOKAWA, Yoshiaki, KOGA, Masatoshi, TOYODA, Kazunori, IGUCHI, Yasuyuki, IWAMA, Toru, YAMAGAMI, Hiroshi, OGASAWARA, Kuniaki, MINEMATSU, Kazuo, TSUJINO, Akira, HATANO, Taketo, TERAYAMA, Yasuo, ITABASHI, Ryo, INOUE, Manabu, HASEGAWA, Yasuhiro, OKADA, Yasushi
• Format: Journal Article
• Language: English
• Published: Japan The Japan Neurosurgical Society 2019; THE JAPAN NEUROSURGICAL SOCIETY; Japan Science and Technology Agency
• Subjects: acute ischemic stroke; alteplase; Guideline; Intravenous administration; Japan; Special Topic; Thrombolysis; thrombolysis; Guideline; alteplase; Japan; acute ischemic stroke

[Preface] In 2005, intravenous (IV) thrombolysis using alteplase, a recombinant tissue, type plasminogen activator (rt-PA), for patients with acute ischemic stroke was approved in Japanon the basis of the results of the Japan Alteplase Clinical Trial (J-ACT) with a specific low-dose regimen. Over th...