Aluminum tolerance in transgenic plants by alteration of citrate synthesis

• Published in: Science (American Association for the Advancement of Science) Vol. 276; no. 5318; pp. 1566 - 1568
• Main Authors: Fuente, J.M. de la (Unidad Irapuato, Guanajuato, Mexico.), Ramirez-Rodriguez, V, Cabrera-Ponce, J.L, Herrera-Estrella, L
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for the Advancement of Science 06.06.1997; American Association for the Advancement of Science; The American Association for the Advancement of Science
• Subjects: Acid soils; Agricultural Production; ALUMINIO; ALUMINIUM; Aluminum; Aluminum (Metal); Aluminum - toxicity; Aluminum content; Biological and medical sciences; BIOSINTESIS; BIOSYNTHESE; CARICA PAPAYA; CITRATE; Citrate (si)-Synthase - genetics; Citrate (si)-Synthase - metabolism; Citrates; Citrates - biosynthesis; CITRATOS; Classical genetics, quantitative genetics, hybrids; Coding; Crops; Flowers & plants; Fruit - drug effects; Fruit - genetics; Fruit - metabolism; Fundamental and applied biological sciences. Psychology; Genetic engineering; Genetics of eukaryotes. Biological and molecular evolution; Inhibition; Nicotiana - drug effects; Nicotiana - genetics; Nicotiana - metabolism; NICOTIANA TABACUM; Nutrient solutions; Nutrition; Plant genetic engineering; Plant roots; Plant Roots - drug effects; Plant Roots - growth & development; PLANTAS TRANSGENICAS; PLANTE TRANSGENIQUE; Plants; Plants - drug effects; Plants - genetics; Plants - metabolism; Plants, Genetically Modified; Plants, Toxic; Pseudomonas aeruginosa - enzymology; Pseudomonas aeruginosa - genetics; Pteridophyta, spermatophyta; RESISTANCE AUX FACTEURS NUISIBLES; RESISTENCIA A AGENTES DANINOS; Root growth; Seedlings; Seeds - drug effects; Seeds - growth & development; Soil chemistry; Soils; Statistical Analysis; Transgenic plants; Vegetals; Water; Enzyme; Gene overexpression; Caricaceae; Lyases; Aluminium; Gene expression; Metabolism; Nicotiana tabacum; Heavy metal; Oxo-acid-lyases; Resistance; Carbon-carbon lyases; Citrate (si)-synthase; Gene; Dicotyledones; Angiospermae; Spermatophyta; Transgenic plant; Solanaceae; Fruit tree; Carica papaya
• ISSN: 0036-8075; 1095-9203
• DOI: 10.1126/science.276.5318.1566

Aluminum when in soluble form, as found in acidic soils that comprise about 40 percent of the world's arable land, is toxic to many crops. Organic acid excretion has been correlated with aluminum tolerance in higher plants. Overproduction of citrate was shown to result in aluminum tolerance in transgenic tobacco (Nicotiana tabacum) and papaya (Carica papaya) plants