Candida albicans Biofilms Produce More Secreted Aspartyl Protease than the Planktonic Cells

By using a simple, low-cost system of polystyrene centrifuge tubes we compared the secreted aspartyl proteases (Saps) secretion during the biphasic growth modes of Candida albicans using twenty-one clinical isolates. Our results indicate that biofilms of C. albicans consistently secrete more Saps th...

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Bibliographic Details
Published inBiological & Pharmaceutical Bulletin Vol. 30; no. 9; pp. 1813 - 1815
Main Authors Mendes, Aline, Mores, Alinne Ulbrich, Carvalho, Alessandra Paula, Rosa, Rosimeire Takaki, Samaranayake, Lakshman Perera, Rosa, Edvaldo Antonio Ribeiro
Format Journal Article
LanguageEnglish
Japanese
Published Japan The Pharmaceutical Society of Japan 01.09.2007
Pharmaceutical Society of Japan
Japan Science and Technology Agency
Subjects
Aspartic Acid Endopeptidases - metabolism
biofilm
Biofilms
Biomass
Candida albicans
Candida albicans - enzymology
Candida albicans - growth & development
Candida albicans - physiology
Mitochondria - enzymology
planktonic
secreted aspartyl protease (Sap)
Tetrazolium Salts
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Summary:By using a simple, low-cost system of polystyrene centrifuge tubes we compared the secreted aspartyl proteases (Saps) secretion during the biphasic growth modes of Candida albicans using twenty-one clinical isolates. Our results indicate that biofilms of C. albicans consistently secrete more Saps than their planktonic counterparts.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0918-6158
1347-5215
DOI:10.1248/bpb.30.1813