Effects of Liver-Supplemented Food on the Development of Embryos in Mice

• Published in: Biological & Pharmaceutical Bulletin Vol. 26; no. 4; pp. 553 - 556
• Main Authors: Akase, Tomoko, Yamashina, Shohei, Akase, Tomohide, Onodera, Satoshi, Okuda, Hirokazu, Tashiro, Shin-ichi
• Format: Journal Article
• Language: English; Japanese
• Published: Tokyo The Pharmaceutical Society of Japan 2003; Pharmaceutical Society of Japan; Maruzen; Japan Science and Technology Agency
• Subjects: Animals; Biological and medical sciences; Cattle; Dietary Supplements; Embryonic and Fetal Development - drug effects; Embryonic and Fetal Development - physiology; Female; fetal abnormality; food supplement; Liver; Liver Extracts - pharmacology; Liver Extracts - toxicity; Male; Medical sciences; Mice; Mice, Inbred ICR; Pregnancy; retinol palmitate; vitamin A; Vitamin A - pharmacology; Vitamin A - toxicity; food supplement; vitamin A; retinol palmitate; liver; fetal abnormality

We examined whether dietary intake of cattle liver-supplemented food induces reproductive effects in dams and developmental effects in embryos in the mouse model. Seven groups of 19 to 35 female mice each were given either powdered food or the food supplemented with crude liver homogenate, its lipop...