Serologic and molecular evidence for circulation of Crimean-Congo hemorrhagic fever virus in ticks and cattle in Zambia

• Published in: PLoS neglected tropical diseases Vol. 15; no. 6; p. e0009452
• Main Authors: Kajihara, Masahiro, Simuunza, Martin, Saasa, Ngonda, Dautu, George, Mori-Kajihara, Akina, Qiu, Yongjin, Nakao, Ryo, Eto, Yoshiki, Furumoto, Hayato, Hang’ombe, Bernard M., Orba, Yasuko, Sawa, Hirofumi, Simulundu, Edgar, Fukushi, Shuetsu, Morikawa, Shigeru, Saijo, Masayuki, Arikawa, Jiro, Kabilika, Swithine, Monze, Mwaka, Mukonka, Victor, Mweene, Aaron, Takada, Ayato, Yoshimatsu, Kumiko
• Format: Journal Article
• Language: English
• Published: San Francisco Public Library of Science 01.06.2021; Public Library of Science (PLoS)
• Subjects: Animals; Annealing; Arachnids; Biology and Life Sciences; Cattle; Computer and Information Sciences; Crimean hemorrhagic fever; Disease transmission; Distribution; Epidemiology; Fever; Genetic aspects; Genetic diversity; Genetic variation; Genomes; Genotype; Haemorrhage; Health aspects; Hemorrhage; Identification and classification; Immunofluorescence; Immunoglobulin G; Infections; Infectious diseases; Laboratories; Medicine and health sciences; Methods; Microbiological strains; People and Places; Phylogeny; Risk assessment; RNA polymerase; Sentinel health events; Serum; Strains; Ticks; Transmission; Tropical diseases; Vertebrates; Veterinary medicine; Virus-vector relationships; Viruses; Zoonoses; Zambia

Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne zoonosis with a high case fatality rate in humans. Although the disease is widely found in Africa, Europe, and Asia, the distribution and genetic diversity of CCHF virus (CCHFV) are poorly understood in African countries. To assess the risks of...