Structure of Actinotetraose Hexatiglate, a Unique Glucotetraose from an Actinomycete Bacterium

• Published in: Journal of antibiotics Vol. 51; no. 12; pp. 1093 - 1098
• Main Authors: RICKARDS, R. W., ROTHSCHILD, J. M., LACEY, E.
• Format: Journal Article
• Language: English
• Published: TOKYO JAPAN ANTIBIOTICS RESEARCH ASSOCIATION 1998; JAPAN ANTIBIOT RES ASSN; Japan Antibiotics Research Association
• Subjects: Actinomycetales - chemistry; Actinomycetales - classification; Actinomycetales - isolation & purification; Amycolata; Amycolatopsis; Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - isolation & purification; Antibiotics; Biological and medical sciences; Biotechnology; Biotechnology & Applied Microbiology; Carbohydrate Sequence; Chemical Phenomena; Chemistry, Physical; Crotonates - chemistry; Crotonates - isolation & purification; Echinomycin - analogs & derivatives; Echinomycin - chemistry; Echinomycin - isolation & purification; Fundamental and applied biological sciences. Psychology; Health. Pharmaceutical industry; Immunology; Industrial applications and implications. Economical aspects; Life Sciences & Biomedicine; Magnetic Resonance Spectroscopy; Microbiology; Molecular Sequence Data; Molecular Structure; Oligosaccharides - chemistry; Oligosaccharides - isolation & purification; Pharmacology & Pharmacy; Production of active biomolecules; Science & Technology; Soil Microbiology; Spectrometry, Mass, Fast Atom Bombardment; Antibiotic; Production; Chemical structure; Bacteria; Isolation; Actinomycetes; Physicochemical properties; Tetrasaccharide
• ISSN: 0021-8820; 1881-1469
• DOI: 10.7164/antibiotics.51.1093

An Actinomycete strain A499 belonging to the genera Amycolatopsis or Amycolata isolated from a Western Australian soil sample produced the cyclic decapeptide antibiotic quinaldopeptin (1), together with the actinotetraose hexatiglate (2), the hexa-ester of a novel non-reducing glucotetraose.