The genetic covariance between life cycle stages separated by metamorphosis

• Published in: Proceedings of the Royal Society. B, Biological sciences Vol. 281; no. 1788; p. 20141091
• Main Authors: Aguirre, J. David, Blows, Mark W., Marshall, Dustin J.
• Format: Journal Article
• Language: English
• Published: England The Royal Society 07.08.2014
• Subjects: Adaptive Decoupling; Animals; Ciona; Ciona intestinalis - genetics; Ciona intestinalis - growth & development; Embryo, Nonmammalian - embryology; Genetic Fitness; Genetic Variance–covariance Matrix; Genetic Variation; Larva - genetics; Larva - growth & development; Life Cycle Stages; Life-History Evolution; Metamorphosis, Biological; South Australia; Target Matrix Rotation; South Australia; adaptive decoupling; genetic variance–covariance matrix; Ciona; target matrix rotation; life-history evolution
• ISSN: 0962-8452; 1471-2954; 1471-2945; 1471-2954
• DOI: 10.1098/rspb.2014.1091

Metamorphosis is common in animals, yet the genetic associations between life cycle stages are poorly understood. Given the radical changes that occur at metamorphosis, selection may differ before and after metamorphosis, and the extent that genetic associations between pre- and post-metamorphic traits constrain evolutionary change is a subject of considerable interest. In some instances, metamorphosis may allow the genetic decoupling of life cycle stages, whereas in others, metamorphosis could allow complementary responses to selection across the life cycle. Using a diallel breeding design, we measured viability at four ontogenetic stages (embryo, larval, juvenile and adult viability), in the ascidian Ciona intestinalis and examined the orientation of additive genetic variation with respect to the metamorphic boundary. We found support for one eigenvector of G (gobsmax), which contrasted larval viability against embryo viability and juvenile viability. Target matrix rotation confirmed that while gobsmax shows genetic associations can extend beyond metamorphosis, there is still considerable scope for decoupled phenotypic evolution. Therefore, although genetic associations across metamorphosis could limit that range of phenotypes that are attainable, traits on either side of the metamorphic boundary are capable of some independent evolutionary change in response to the divergent conditions encountered during each life cycle stage.