Experimental infection of recent field isolates of feline herpesvirus type 1

• Published in: Journal of Veterinary Medical Science Vol. 65; no. 8; pp. 939 - 943
• Main Authors: Hamano, M. (Yamaguchi Univ. (Japan). Faculty of Agriculture), Maeda, K, Mizukoshi, F, Une, Y, Mochizuki, M, Tohya, Y, Akashi, H, Kai, K
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 01.08.2003; Japan Science and Technology Agency
• Subjects: Animals; Body Temperature; Body Weight; Cat Diseases - physiopathology; Cat Diseases - virology; CATS; CONJUNCTIVITIS; Conjunctivitis - veterinary; Conjunctivitis - virology; FELINE HERPESVIRUS; Feline herpesvirus 1; feline herpesvirus type 1; FELINE RHINOTRACHEITIS VIRUS; feline viral rhinotracheitis; Hemorrhage - veterinary; Hemorrhage - virology; Herpesviridae Infections - physiopathology; Herpesviridae Infections - veterinary; Herpesvirus; Time Factors; Varicellovirus - isolation & purification; Varicellovirus - pathogenicity
• ISSN: 0916-7250; 1347-7439
• DOI: 10.1292/jvms.65.939

Two field isolates of feline herpesvirus type 1 (FHV-1) designated as 00-015 and 00-035, were obtained from cats diagnosed as feline viral rhinotracheitis (FVR) in Japan. To analyze the character of recent FHV-1, these two isolates and our laboratory strain C7301 were inoculated experimentally to specific-pathogen-free cats. Although all cats showed typical FVR symptoms, more severe clinical symptoms were observed on cats infected with the isolates 00-015 and 00-035 compared with those of C7301-infected cats. Severe ocular lesions including conjunctivitis were found in the cats infected with the isolates, indicating that the recent FHV-1 has a potential to induce severe FVR symptoms including ocular lesions.