Porencephaly in dogs and cats: relationships between magnetic resonance imaging (MRI) features and hippocampal atrophy

• Published in: Journal of Veterinary Medical Science Vol. 77; no. 7; pp. 889 - 892
• Main Authors: HORI, Ai, HANAZONO, Kiwamu, MIYOSHI, Kenjirou, NAKADE, Tetsuya
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 01.07.2015; The Japanese Society of Veterinary Science
• Subjects: Animals; Atrophy; canine; Cat Diseases - diagnosis; Cat Diseases - pathology; Cats; Dog Diseases - diagnosis; Dog Diseases - pathology; Dogs; feline; Female; hippocampus; Hippocampus - pathology; Magnetic Resonance Imaging - veterinary; Male; MRI; porencephaly; Porencephaly - diagnosis; Porencephaly - pathology; Porencephaly - veterinary; Surgery
• ISSN: 0916-7250; 1347-7439
• DOI: 10.1292/jvms.14-0359

Porencephaly is the congenital cerebral defect and a rare malformation and described few MRI reports in veterinary medicine. MRI features of porencephaly are recognized the coexistence with the unilateral/bilateral hippocampal atrophy, caused by the seizure symptoms in human medicine. We studied 2 dogs and 1 cat with congenital porencephaly to characterize the clinical signs and MRI, and to discuss the associated MRI with hippocampal atrophy. The main clinical sign was the seizure symptoms, and all had hippocampal atrophy at the lesion side or the larger defect side. There is association between hippocampal atrophy or the cyst volume and the severe of clinical signs, and it is suggested that porencephaly coexists with hippocampal atrophy as well as humans in this study.