Severe Thrombocytopenia after Zika Virus Infection, Guadeloupe, 2016

• Published in: Emerging infectious diseases Vol. 23; no. 4; pp. 696 - 698
• Main Authors: Boyer Chammard, Timothée, Schepers, Kinda, Breurec, Sébastien, Messiaen, Thierry, Destrem, Anne-Laure, Mahevas, Matthieu, Soulillou, Adrien, Janaud, Ludovic, Curlier, Elodie, Herrmann-Storck, Cécile, Hoen, Bruno
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01.04.2017; Centers for Disease Control and Prevention
• Subjects: Adolescent; Adult; Aged; Child, Preschool; Complications and side effects; Disease transmission; Dispatch; Expedited; Female; Guadeloupe; Guadeloupe - epidemiology; Guillain-Barre syndrome; Hemorrhage - etiology; hemorrhagic symptoms; Humans; infection; Life Sciences; Male; Middle Aged; Santé publique et épidémiologie; Severe Thrombocytopenia after Zika Virus Infection, Guadeloupe, 2016; Thrombocytopenia; Thrombocytopenia - etiology; Thrombocytopenia - pathology; viruses; Zika virus; Zika Virus Infection - complications; Zika Virus Infection - epidemiology; France; Guadeloupe; infection; viruses; hemorrhagic signs and symptoms; thrombocytopenia; Guadeloupe; Zika virus; Zika
• ISSN: 1080-6040; 1080-6059
• DOI: 10.3201/eid2304.161967

Severe thrombocytopenia during or after the course of Zika virus infection has been rarely reported. We report 7 cases of severe thrombocytopenia and hemorrhagic signs and symptoms in Guadeloupe after infection with this virus. Clinical course and laboratory findings strongly suggest a causal link between Zika virus infection and immune-mediated thrombocytopenia.