Suppression of distracting inputs by visual-spatial cues is driven by anticipatory alpha activity

• Published in: PLoS biology Vol. 21; no. 3; p. e3002014
• Main Authors: Zhao, Chenguang, Kong, Yuanjun, Li, Dongwei, Huang, Jing, Kong, Lujiao, Li, Xiaoli, Jensen, Ole, Song, Yan
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 08.03.2023; Public Library of Science (PLoS)
• Subjects: Accuracy; Analysis; Attention; Attention - physiology; Behavior; Biology and Life Sciences; Cues; Dynamic characteristics; EEG; Efficiency; Electroencephalography; Experiments; Humans; Hypotheses; Inhibition, Psychological; Interference; Medicine and Health Sciences; Methods; Physical Sciences; Reaction Time - physiology; Research and Analysis Methods; Social Sciences; Spatial analysis (Statistics); Validity; Visual Perception - physiology; Visual stimuli; United Kingdom
• ISSN: 1545-7885; 1544-9173; 1545-7885
• DOI: 10.1371/journal.pbio.3002014

A growing body of research demonstrates that distracting inputs can be proactively suppressed via spatial cues, nonspatial cues, or experience, which are governed by more than one top-down mechanism of attention. However, how the neural mechanisms underlying spatial distractor cues guide proactive suppression of distracting inputs remains unresolved. Here, we recorded electroencephalography signals from 110 participants in 3 experiments to identify the role of alpha activity in proactive distractor suppression induced by spatial cues and its influence on subsequent distractor inhibition. Behaviorally, we found novel changes in the spatial proximity of the distractor: Cueing distractors far away from the target improves search performance for the target, while cueing distractors close to the target hampers performance. Crucially, we found dynamic characteristics of spatial representation for distractor suppression during anticipation. This result was further verified by alpha power increased relatively contralateral to the cued distractor. At both the between- and within-subjects levels, we found that these activities further predicted the decrement of the subsequent P D component, which was indicative of reduced distractor interference. Moreover, anticipatory alpha activity and its link with the subsequent P D component were specific to the high predictive validity of distractor cue. Together, our results reveal the underlying neural mechanisms by which cueing the spatial distractor may contribute to reduced distractor interference. These results also provide evidence supporting the role of alpha activity as gating by proactive suppression.