Racial Differences in the Cholesterol-Lowering Effect of Statin

Statin treatment to reduce low-density lipoprotein cholesterol (LDL-C) is associated with the prevention of cardiovascular events in Western patients. Similar results have been reported in studies conducted in Japan. However, the dose of statins and the degree of LDL-C reduction achieved with statin...

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Bibliographic Details
Published inJournal of Atherosclerosis and Thrombosis Vol. 24; no. 1; pp. 19 - 25
Main Authors Naito, Ryo, Daida, Hiroyuki, Miyauchi, Katsumi
Format Journal Article
LanguageEnglish
Published Japan Japan Atherosclerosis Society 01.01.2017
Subjects
Anticholesteremic Agents - pharmacology
Asian
Cardiovascular Diseases - drug therapy
Cardiovascular Diseases - ethnology
Cholesterol, LDL - metabolism
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology
Racial differences
Racial Groups - statistics & numerical data
Review
Statin
Westerner
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ISSN1340-3478
1880-3873
DOI10.5551/jat.RV16004

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Summary:Statin treatment to reduce low-density lipoprotein cholesterol (LDL-C) is associated with the prevention of cardiovascular events in Western patients. Similar results have been reported in studies conducted in Japan. However, the dose of statins and the degree of LDL-C reduction achieved with statins are different between Asian and Western patients. In addition, there are limited data regarding racial differences in response to statins. In this review, racial differences between Asians and Westerners in response to statins are described.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:1340-3478
1880-3873
DOI:10.5551/jat.RV16004