Application of radiomics in osteoporosis detection — current capabilities and future prospects (a review)

• Published in: Digital diagnostics Vol. 6; no. 1; pp. 63 - 77
• Main Authors: Chugaev, Anton I., Vasilev, Yuriy A., Petraikin, Alexey V., Blokhin, Ivan A., Vladzymyrskyy, Anton V., Omelyanskaya, Olga V.
• Format: Journal Article
• Language: English
• Published: 25.03.2025
• ISSN: 2712-8490; 2712-8962
• DOI: 10.17816/DD635014

The prevalence of osteoporotic fractures continues to increase as the population ages due to demographic transition. This is particularly relevant for developed countries, including Russia. Radiomics may emerge as a valuable tool for osteoporosis detection. This review demonstrates the development and application of radiomics in diagnosing oncological and non-oncological diseases including osteoporosis. A literature search was conducted using the databases PubMed, Google Scholar, and eLibrary over the past 5 years. Data on the prevalence and epidemiology of osteoporosis were obtained from publications in the last 15 years. The search was performed using the following keywords: "radiomic", "osteoporosis", "texture", "magnetic resonance imaging", "computed tomography", "non-oncological radiomics", «магнитно-резонансная томография» ("magnetic resonance imaging"), «компьютерная томография» ("computed tomography"), «радиомика» ("radiomics"), «остеопороз» ("osteoporosis"), «текстурный анализ» ("texture analysis"), «радиомический анализ» ("radiomic analysis"). Data from original clinical studies were included. In total, 247 articles were found and analyzed. Finally, 59 studies were selected for the review. The number of studies examining the potential of radiomics in detecting osteoporosis was limited. Further research is required to explore the potential of radiomic analysis using computed tomography and magnetic resonance imaging for detecting osteoporosis compared to established methods such as dual-energy X-ray absorptiometry and the FRAX (Fracture Risk Assessment Tool) algorithm.