Computed Tomography of Aortic Wall Calcifications in Aortic Dissection Patients

• Published in: PloS one Vol. 9; no. 7; p. e102036
• Main Authors: de Jong, Pim A., Hellings, Willem E., Takx, Richard A. P., Išgum, Ivana, van Herwaarden, Joost A., Mali, Willem P. Th. M.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 08.07.2014; Public Library of Science (PLoS)
• Subjects: Abdomen; Age; Aged; Aged, 80 and over; Aorta; Aorta - pathology; Aortic Aneurysm - diagnostic imaging; Aortic dissection; Aortography; Arteriosclerosis; Atherosclerosis; Calcification; CAT scans; Computed tomography; Coronary vessels; Diabetes; Diabetic neuropathy; Female; Humans; Hypertension; Male; Medical imaging; Medicine and Health Sciences; Metabolic disorders; Patients; Population studies; Reliability analysis; Retrospective Studies; Statistical tests; Surgery; Tomography, X-Ray Computed; Tunica Intima - pathology; Vascular Calcification - diagnostic imaging; Vascular surgery; Veins & arteries; Netherlands
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0102036

To investigate the frequency of aortic calcifications at the outer edge of the false lumen and the frequency of fully circular aortic calcifications in a consecutive series of patients with aortic dissection who underwent contrast-enhanced CT. The study population compromised of 69 consecutive subjects aged 60 years and older with a contrast-enhanced CT scan demonstrating an aortic dissection. All CT scans were evaluated for the frequency of aortic calcifications at the outer edge of the false lumen and the frequency of fully circular aortic calcifications by two experienced observers. Between observer reliability was evaluated by using Cohen's Kappa. Differences between groups were tested using unpaired T test and Chi-square test. Presumed media calcifications were observed in 22 (32%) patients of 60 years and older and were found more frequently in chronic aortic dissection (N = 12/23, 52%) than in acute aortic dissection (N = 10/46, 22%). As the intima has been torn away by the aortic dissection it is highly likely that CT scans can visualize the calcifications in the tunica media of the aorta.