The Associations of Single Nucleotide Polymorphisms in miR-146a, miR-196a and miR-499 with Breast Cancer Susceptibility

• Published in: PloS one Vol. 8; no. 9; p. e70656
• Main Authors: Wang, Ping-Yu, Gao, Zong-Hua, Jiang, Zhong-Hua, Li, Xin-Xin, Jiang, Bao-Fa, Xie, Shu-Yang
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 09.09.2013; Public Library of Science (PLoS)
• Subjects: Analysis; Breast cancer; Breast Neoplasms - genetics; Cancer; Case-Control Studies; Chromosomes; Confidence intervals; Disease susceptibility; Epidemiology; Female; Gene Frequency; Genes; Genetic aspects; Genetic Association Studies; Genetic Predisposition to Disease; Genotypes; Health aspects; Health risk assessment; Health risks; Humans; Liver cancer; Medical ethics; Meta-analysis; MicroRNA; MicroRNAs; MicroRNAs - genetics; miRNA; Oncology, Experimental; Polymorphism, Single Nucleotide; Public health; Single nucleotide polymorphisms; Single-nucleotide polymorphism; Statistical analysis; Studies; Xin Li; China

Previous studies have investigated the association between single nucleotide polymorphisms (SNPs) located in microRNAs (miRNAs) and breast cancer susceptibility; however, because of their limited statistical power, many discrepancies are revealed in these studies. The meta-analysis presented here ai...