Chest wall volume and asynchrony in stroke and Parkinson’s disease subjects: A case-control study

• Published in: PloS one Vol. 14; no. 5; p. e0216641
• Main Authors: Florêncio, Rêncio Bento, da Nobrega, Antonio José Sarmento, Lima, Íllia Nadinne Dantas Florentino, Gualdi, Lucien Peroni, Cabral, Elis Emmanuelle, Fagundes, Marina Lyra Lima Cabral, Aliverti, Andrea, Resqueti, Vanessa Regiane, Fregonezi, Guilherme Augusto de Freitas
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 16.05.2019; Public Library of Science (PLoS)
• Subjects: Abdomen; Aged; Biology and Life Sciences; Breathing; Cages; Case-Control Studies; Chest; Contraction; Diagnosis; Diaphragm; Diaphragm (anatomy); Disease control; Female; Humans; Laboratories; Lung - physiopathology; Lung diseases; Male; Medical research; Medicine and Health Sciences; Middle Aged; Muscle contraction; Muscles; Optoelectronics; Organ Size; Parkinson disease; Parkinson Disease - pathology; Parkinson Disease - physiopathology; Parkinson's disease; Pattern analysis; Plethysmography; Position measurement; Respiration; Respiratory diseases; Respiratory Mechanics - physiology; Respiratory Muscles - physiopathology; Respiratory tract diseases; Rib; Ribs; Stroke; Stroke - pathology; Stroke - physiopathology; Thoracic Wall - pathology; Thoracic Wall - physiopathology; Rio Grande do Norte Brazil; Brazil
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0216641

The expansion of the rib cage and abdomen occurs in a synchronic way during a coordinated contraction of the diaphragm and the abdominal and intercostal muscles under normal conditions and healthy. The presence of restrictive respiratory disease may lead to uncoordinated action of the respiratory muscles which affects breathing pattern and chest wall volumes. The aim of this study was to evaluate chest wall volumes, chest wall asynchrony and inspiratory paradoxical movement of breathing, as well as the influence of the time of disease diagnosis in subjects with Parkinson's disease and post-Stroke in comparison to healthy individuals. Total and compartmental chest wall volumes, chest wall asynchrony and paradoxical movement were measured at rest in a seated position by Optoelectronic Plethysmography in 76 individuals (29 healthy individuals, 20 post-Stroke and 27 Parkinson's disease subjects). Post-stroke and Parkinson's disease subjects were also grouped according to the length of diagnosis. In both groups with restrictive respiratory disease we observed that pulmonary rib cage compartment (VRCp) volume is reduced when compared to healthy subjects (p <0.05). This same pattern was observed when analyzing post-stroke subjects with more than three years of diagnosis and Parkinson's subjects with less than three years of diagnosis (p<0.05). Furthermore, post-stroke subjects with inspiratory paradoxical movement showed decreased total and compartmental chest wall volumes (p<0.05), while individuals with Parkinson's disease with inspiratory paradoxical movement only presented a decrease in pulmonary rib cage compartment volume (p<0.05). Our study presents new findings for better understanding of chest wall volumes and chest wall asynchrony in post-stroke and Parkinson's disease individuals. Half of the subjects with post-Stroke and Parkinson's disease presented inspiratory paradox movement, but changes in breathing pattern was especially observed in post-stroke subjects with more than three years of diagnosis.