Quality of pharmaceutical care in surgical patients

• Published in: PloS one Vol. 9; no. 7; p. e101573
• Main Authors: de Boer, Monica, Ramrattan, Maya A, Boeker, Eveline B, Kuks, Paul F M, Boermeester, Marja A, Lie-A-Huen, Loraine
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 09.07.2014; Public Library of Science (PLoS)
• Subjects: Adolescent; Adult; Aged; Analgesics - adverse effects; Analgesics - therapeutic use; Cohort Studies; Drug stores; Drugs; Elective Surgical Procedures; Feasibility studies; Female; Gastrointestinal Diseases - chemically induced; Health care; Health care facilities; Hospital patients; Hospitals; Humans; Indicators; Inpatients; Intestine; Male; Medical care quality; Medical records; Medication Errors; Medicine and Health Sciences; Middle Aged; Patient care; Patient safety; Patients; Pharmaceuticals; Pharmacists; Pharmacy Service, Hospital - standards; Physicians; Problems; Quality; Quality assessment; Quality Indicators, Health Care; Surgeons; Surgery; Target detection; Young Adult; Netherlands
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0101573

Surgical patients are at risk for preventable adverse drug events (ADEs) during hospitalization. Usually, preventable ADEs are measured as an outcome parameter of quality of pharmaceutical care. However, process measures such as QIs are more efficient to assess the quality of care and provide more information about potential quality improvements. To assess the quality of pharmaceutical care of medication-related processes in surgical wards with quality indicators, in order to detect targets for quality improvements. For this observational cohort study, quality indicators were composed, validated, tested, and applied on a surgical cohort. Three surgical wards of an academic hospital in the Netherlands (Academic Medical Centre, Amsterdam) participated. Consecutive elective surgical patients with a hospital stay longer than 48 hours were included from April until June 2009. To assess the quality of pharmaceutical care, the set of quality indicators was applied to 252 medical records of surgical patients. Thirty-four quality indicators were composed and tested on acceptability and content- and face-validity. The selected 28 candidate quality indicators were tested for feasibility and 'sensitivity to change'. This resulted in a final set of 27 quality indicators, of which inter-rater agreements were calculated (kappa 0.92 for eligibility, 0.74 for pass-rate). The quality of pharmaceutical care was assessed in 252 surgical patients. Nearly half of the surgical patients passed the quality indicators for pharmaceutical care (overall pass rate 49.8%). Improvements should be predominantly targeted to medication care related processes in surgical patients with gastro-intestinal problems (domain pass rate 29.4%). This quality indicator set can be used to measure quality of pharmaceutical care and detect targets for quality improvements. With these results medication safety in surgical patients can be enhanced.