Circulating Betatrophin Correlates with Triglycerides and Postprandial Glucose among Different Glucose Tolerance Statuses—A Case-Control Study

• Published in: PloS one Vol. 10; no. 8; p. e0133640
• Main Authors: Gao, Ting, Jin, Kairui, Chen, Peihong, Jin, Hua, Yang, Lili, Xie, Xinmiao, Yang, Meili, Hu, Cheng, Yu, Xuemei
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 06.08.2015; Public Library of Science (PLoS)
• Subjects: Adult; Alanine; Alanine transaminase; Alanine Transaminase - blood; Angiopoietin-like Proteins; Anthropometry; Aspartate Aminotransferases - blood; Aspartate transaminase; Beta cells; Blood Glucose - analysis; Body mass; Body mass index; Body size; Care and treatment; Case-Control Studies; Cell growth; Correlation; Development and progression; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - diagnosis; Diabetic retinopathy; Diagnosis; Endocrinology; Enzyme-Linked Immunosorbent Assay; Female; Gender; Glucose; Glucose Intolerance - pathology; Glucose metabolism; Glucose tolerance; Glucose Tolerance Test; Hemoglobin; Homeostasis; Hospitals; Humans; Indexing; Insulin; Insulin resistance; Islets of Langerhans; Lipid metabolism; Lipids; Male; Metabolism; Middle Aged; Multiple regression analysis; Obesity; Pancreatic beta cells; Parameters; Patients; Peptide Hormones - blood; Physiological aspects; Postprandial Period; Regression Analysis; Risk factors; Transaminase; Triglycerides; Triglycerides - blood; Type 2 diabetes; United States; United States > US; China

Previous researches of betatrophin on glucose and lipids metabolism under insulin-resistant condition have reached controversial conclusions. To further identify the possible impact of betatrophin, we measured the circulating betatrophin levels in newly diagnosed type 2 diabetes (T2DM) patients, and...