Rosai-Dorfman cutaneous form

Proliferative histiocyte disease, rarely found in the dermatovenerologist practice. Rosai-Dorfman disease is a benign disease of unclear etiology, may be accompanied by cervical nodes extensive lymphadenopathy and extranodal lesion. The absence of pathognomonic signs leads to a long-term diagnostic...

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Published inVestnik dermatologij i venerologij
Main Authors Krasnova, Nadezhda V., Gimalieva, Geliya G., Nikolaeva, Snezhana Yuryevna, Sinitsyna, Larisa G., Koltsova, Irina
Format Journal Article
LanguageEnglish
Published 04.10.2024
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Summary:Proliferative histiocyte disease, rarely found in the dermatovenerologist practice. Rosai-Dorfman disease is a benign disease of unclear etiology, may be accompanied by cervical nodes extensive lymphadenopathy and extranodal lesion. The absence of pathognomonic signs leads to a long-term diagnostic search with diagnosis verification only by histological method. The clinical cases rare description in dermatological practice is an important work aspect and a necessary component of expanding the knowledge and practicing physicians experience. Purpose: to describe the case of the Rosai-Dorfman cutaneous form with differential search. Materials and methods: detailed clinical data analysis, including a symptoms description and changes on the skin, as well as the results of a pathohistological study. The Rosai-Dorfman cutaneous form features and potential pathogenetic mechanisms of the disease are discussed. Currently, there is no specific pathogenetic treatment for the Rosai-Dorfman cutaneous form. The therapy which used was symptomatic and based on the symptoms elimination.
ISSN:0042-4609
2313-6294
DOI:10.25208/vdv16751