Long-Term SARS-CoV-2 Antibody Seroprevalence in Blood Donors, Italy

• Published in: Emerging infectious diseases Vol. 29; no. 7; pp. 1479 - 1481
• Main Authors: Ferrari, Martina, Di Marco, Lorenza, Pivetti, Alessandra, Paduano, Stefania, Vecchi, Chiara, Bernabucci, Veronica, Critelli, Rosina Maria, Lasagni, Simone, De Maria, Monica, Venturelli, Donatella, Pecorari, Monica, Boaretto, Giorgia, Serpini, Giulia Fregni, Romagnoli, Dante, Mantovani, Roberto, Ceccherelli, Giovanni Battista, Villa, Erica
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01.07.2023; Centers for Disease Control and Prevention
• Subjects: Analysis; Antibodies; Antibodies, Viral; Asymptomatic; Blood & organ donations; blood donor population; Blood Donors; Communicable Disease Control; COVID-19; COVID-19 - epidemiology; COVID-19 vaccines; Hay fever; Health aspects; Health care; Humans; Immune response; Immunoglobulin G; Infections; Italy; Italy - epidemiology; Long-Term SARS-CoV-2 Antibody Seroprevalence in Blood Donors, Italy; Pandemics; Public health; Research Letter; Rhinitis; SARS-CoV-2; Seroepidemiologic Studies; serologic analysis; Serology; Severe acute respiratory syndrome coronavirus 2; Statistics; Vaccines; Viral antibodies; Italy; COVID-19; blood donor population; SARS-CoV-2; viruses; Italy; antibodies; serologic analysis; respiratory infections
• ISSN: 1080-6040; 1080-6059
• DOI: 10.3201/eid2907.221745

We evaluated SARS-CoV-2 antibody response in voluntary blood donors in Italy at different timepoints. Immediately after lockdown easing, 908/25,657 donors (3.5%) had low IgG titers against nucleocapsid. In the next 2 years, titers increased despite few COVID-19 symptoms. On multivariate analysis, allergic rhinitis was associated with reduced risk for symptomatic COVID-19.