Influence of Contact Force on Electrochemical Responses of Redox Species Flowing in Nitrocellulose Membrane at Micropyramid Array Electrode

• Published in: Analytical Sciences Vol. 31; no. 7; pp. 729 - 732
• Main Authors: IWASAKI, Wataru, SATHULURI, Ramachandra Rao, NIWA, Osamu, MIYAZAKI, Masaya
• Format: Journal Article
• Language: English
• Published: Singapore The Japan Society for Analytical Chemistry 2015; Springer Nature Singapore; Japan Science and Technology Agency
• Subjects: Analytical Chemistry; Arrays; Cellulose esters; Chemistry; Collodion - chemistry; Contact; contact force; Electrochemical measurement; Electrochemistry - instrumentation; Electrodes; Immunochromatography; lateral flow; Mathematical analysis; Membranes; Membranes, Artificial; Micro-Electrical-Mechanical Systems - instrumentation; Microelectrodes; micropyramid array; Nitrocellulose; Oxidation-Reduction; Surface Properties; Voltammetry; micropyramid array; contact force; Electrochemical measurement; lateral flow
• ISSN: 0910-6340; 1348-2246
• DOI: 10.2116/analsci.31.729

In this study, we developed a micropyramid array electrode that facilitates contact between a nitrocellulose membrane and electrode, which is important to realize a quantitative and sensitive electrochemical detection system for immunochromatography. We evaluated the micropyamid array electrode with our newly developed detection system that can measure contact forces between a membrane and electrode, and also investigated the relationship between redox current and contact forces. By using normal pulse voltammetry, we observed higher reduction currents over a flat surface electrode at lower contact forces with the micropyramid array.