Lung Pathology of Mutually Exclusive Co-infection with SARS-CoV-2 and Streptococcus pneumoniae

• Published in: Emerging infectious diseases Vol. 27; no. 3; pp. 919 - 923
• Main Authors: Tsukamoto, Tetsuya, Nakajima, Noriko, Sakurai, Aki, Nakajima, Masayuki, Sakurai, Eiko, Sato, Yuko, Takahashi, Kenta, Kanno, Takayuki, Kataoka, Michiko, Katano, Harutaka, Iwata, Mitsunaga, Doi, Yohei, Suzuki, Tadaki
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01.03.2021; Centers for Disease Control and Prevention
• Subjects: Aged, 80 and over; Autopsy; Bacterial infections; Bacterial pneumonia; Case studies; Coinfection; Comorbidity; coronavirus disease; Coronaviruses; COVID-19; COVID-19 - pathology; Development and progression; Dispatch; Histopathology; Humans; Lung - microbiology; Lung - pathology; Lung - virology; Lung Pathology of Mutually Exclusive Co-infection with SARS-CoV-2 and; Male; Pathology; Pneumococcal Infections - pathology; Pneumonia; Respiratory failure; SARS-CoV-2; SARS-CoV-2 - isolation & purification; Severe acute respiratory syndrome coronavirus 2; Streptococcus infections; Streptococcus pneumoniae; Streptococcus pneumoniae - isolation & purification; Japan; bronchopneumonia; viruses; bacteria; co-infection; Streptococcus pneumoniae; streptococci; COVID-19; SARS-CoV-2; severe acute respiratory syndrome coronavirus 2; acute respiratory distress syndrome; coronavirus disease; autopsy; ARDS
• ISSN: 1080-6040; 1080-6059; 1080-6059
• DOI: 10.3201/eid2703.204024

Postmortem lung pathology of a patient in Japan with severe acute respiratory syndrome coronavirus 2 infection showed diffuse alveolar damage as well as bronchopneumonia caused by Streptococcus pneumoniae infection. The distribution of each pathogen and the accompanying histopathology suggested the infections progressed in a mutually exclusive manner within the lung, resulting in fatal respiratory failure.