Cardiac MR Imaging of Hypertrophic Cardiomyopathy: Techniques, Findings, and Clinical Relevance

Hypertrophic cardiomyopathy (HCM) is a relatively common myocardial genetic disease having a wide variety of symptoms and prognoses. The most serious complications of HCM are sudden cardiac death induced by ventricular arrhythmia or inappropriate changes in blood pressure, and heart failure. Cardiac...

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Published inMagnetic Resonance in Medical Sciences Vol. 17; no. 2; pp. 120 - 131
Main Authors Amano, Yasuo, Kitamura, Mitsunobu, Takano, Hitoshi, Yanagisawa, Fumi, Tachi, Masaki, Suzuki, Yasuyuki, Kumita, Shinichiro, Takayama, Morimasa
Format Journal Article
LanguageEnglish
Published Japan Japanese Society for Magnetic Resonance in Medicine 01.01.2018
Japan Science and Technology Agency
Subjects
Arrhythmia
Blood pressure
cardiac magnetic resonance imaging
Cardiomyopathy
Complications
Fibrosis
Gadolinium
Gene mapping
Heart
Heart diseases
hypertrophic cardiomyopathy
Imaging techniques
late gadolinium enhancement
Magnetic resonance imaging
Physical characteristics
Prognosis
Review
Risk management
steady-state free precession
Ventricle
Wall thickness
steady-state free precession
hypertrophic cardiomyopathy
late gadolinium enhancement
cardiac magnetic resonance imaging
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Summary:Hypertrophic cardiomyopathy (HCM) is a relatively common myocardial genetic disease having a wide variety of symptoms and prognoses. The most serious complications of HCM are sudden cardiac death induced by ventricular arrhythmia or inappropriate changes in blood pressure, and heart failure. Cardiac MR imaging is a valuable imaging method for detecting HCM because of its accurate measurement of wall thickness and myocardial mass without limited view and the unique ability of late gadolinium enhancement (LGE) to identify myocardial fibrosis related to the prognosis of HCM. Tagging and T1 or T2 mapping MR imaging techniques have emerged as quantitative methods for the evaluation of disease severity. In this review, we introduce the MR imaging techniques applied to HCM and demonstrate the typical phenotypes and some morphological characteristics of HCM. In addition, we discuss the clinical relevance of MR imaging for risk stratification and management of HCM.
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ISSN:1347-3182
1880-2206
DOI:10.2463/mrms.rev.2017-0145