Trace Determination of Cyanocobalamin (Vitamin B12) by Analyzing Cobalt Using a Portable Total-Reflection X-ray Fluorescence Spectrometer

A method is presented for the detection of a trace amount of cyanocobalamin (vitamin B12) using a combination of solid-phase extraction and the measurement of cobalt in vitamin B12 by a portable total-reflection X-ray fluorescence spectrometer. Using this combination, a detection limit of 1 ng/mL wa...

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Bibliographic Details
Published inAnalytical Sciences Vol. 34; no. 12; pp. 1401 - 1404
Main Authors KUNIMURA, Shinsuke, TOKUOKA, Yoshie, AONO, Umina
Format Journal Article
LanguageEnglish
Published Singapore The Japan Society for Analytical Chemistry 10.12.2018
Springer Nature Singapore
Japan Science and Technology Agency
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Summary:A method is presented for the detection of a trace amount of cyanocobalamin (vitamin B12) using a combination of solid-phase extraction and the measurement of cobalt in vitamin B12 by a portable total-reflection X-ray fluorescence spectrometer. Using this combination, a detection limit of 1 ng/mL was achieved for vitamin B12.
Bibliography:ObjectType-Article-1
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ISSN:0910-6340
1348-2246
DOI:10.2116/analsci.18P330