Improvement of Signal Inhomogeneity Induced by Radio-frequency Transmit-related Phase Error for Single-step Quantitative Susceptibility Mapping Reconstruction

• Published in: Magnetic Resonance in Medical Sciences Vol. 18; no. 4; pp. 276 - 285
• Main Authors: Kan, Hirohito, Arai, Nobuyuki, Takizawa, Masahiro, Kasai, Harumasa, Kunitomo, Hiroshi, Hirose, Yasujiro, Shibamoto, Yuta
• Format: Journal Article
• Language: English
• Published: Japan Japanese Society for Magnetic Resonance in Medicine 01.01.2019; Japan Science and Technology Agency
• Subjects: Algorithms; Brain; Brain - diagnostic imaging; Brain mapping; Brain Mapping - methods; Humans; Image Processing, Computer-Assisted - methods; Inhomogeneity; Magnetic Resonance Imaging; Mapping; Phase error; quantitative susceptibility mapping; Radio signals; Reconstruction; Signal Processing, Computer-Assisted; single-step quantitative susceptibility mapping; susceptibility inhomogeneity; Technical Note; quantitative susceptibility mapping; single-step quantitative susceptibility mapping; susceptibility inhomogeneity
• ISSN: 1347-3182; 1880-2206
• DOI: 10.2463/mrms.tn.2018-0066

To mitigate the susceptibility inhomogeneity induced by radio-frequency transmit phase error through the whole brain in quantitative susceptibility mapping (QSM) using single-echo gradient echo sequence, we developed a novel single-step QSM reconstruction algorithm and compared it with a previous algorithm in five healthy volunteers. The proposed algorithm had effectively suppressed the susceptibility inhomogeneity through the whole brain and achieved acceptable quality, similar to that of the susceptibility map calculated from a multi-echo gradient echo sequence.