Systemic-Related Factors of Nonarteritic Anterior Ischemic Optic Neuropathy

• Published in: Chinese medical journal Vol. 131; no. 19; pp. 2357 - 2359
• Main Authors: Xiao, Yue-Yan, Wei, Wen-Bin, Wang, Ya-Xing, Lu, Ai-Dong, Chen, Shuo-Hua, Song, Lu, Wu, Shou-Ling
• Format: Journal Article
• Language: English
• Published: China Wolters Kluwer India Pvt. Ltd 05.10.2018; Medknow Publications and Media Pvt. Ltd; Lippincott Williams & Wilkins Ovid Technologies; Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology and Visual Sciences Key Laboratory,Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China; Department of Ophthalmology, Beijing Airport Hospital, Beijing 101318, China%Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology and Visual Sciences Key Laboratory,Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China%Department of Ophthalmology, Kailuan General Hospital, Tangshan, Hebei 063000, China%Department of Cardiology, Kailuan General Hospital, Tangshan, Hebei 063000, China%Department of Respiratory, Kailuan General Hospital, Tangshan, Hebei 063000, China; Medknow Publications & Media Pvt Ltd; Wolters Kluwer
• Subjects: Age; Automation; Body mass index; Brain cancer; Cardiovascular disease; Comorbidity; Correspondence; Defects; Diabetes; Edema; Gender; Hospitals; Hypertension; Medical records; Stroke; Veins & arteries; Beijing China; China
• ISSN: 0366-6999; 2542-5641; 2542-5641
• DOI: 10.4103/0366-6999.241795

Exclusion criteria were as follows: (1) other diseases that can cause edema of the optic disc, such as a brain tumor; (2) other ocular diseases that can cause VF defects, such as retinal detachment, vitreous hemorrhage, and glaucoma; (3) complications from systemic autoimmune diseases; (4) any evidence suggestive of temporal arteritis, such as a history of scalp tenderness, Westergren sedimentation rate ≥40 mm/h, or positive C-reactive protein; and (5) those without a detailed medical record. There were 101,510 patients in the Kailuan study group in 2006. [...]the other 101,472 patients served as the control group. Single variable logistic regression analysis showed that BMI (P = 0.023, odds ratio [OR] = 1.113, 95% confidence interval [CI]: 1.015–1.220), FPG (P < 0.001, OR = 1.221, 95% CI: 1.105–1.349), hyperlipidemia (P = 0.015, OR = 0.453, 95% CI: 0.240–0.855), and stroke history (P < 0.001, OR = 12.012, 95% CI: 5.680–25.400) showed significant differences between the two groups. DFL20150201), the National Natural Science Foundation of China (Nos. 81570891 and 81272981), Beijing Natural Science Foundation (No. 7151003), Advanced Health Care Professionals Development Project of Beijing Municipal Health Bureau (No. 2014-2-003), Study on Individual Diagnosis and Therapy Strategy for Malignant Uveal Melanoma (No. 2016-1-2051), Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support (No.