Sweat is a most efficient natural moisturizer providing protective immunity at points of allergen entry

Although there is a growing acceptance that sweat could play a detrimental role in various allergic skin diseases, the possibility that sweat is also involved in maintenance of skin hydration and skin-specific immune responses has not been acknowledged. We initially describe physiological role of sw...

Full description

Saved in:
Bibliographic Details
Published inAllergology International Vol. 67; no. 4; pp. 442 - 447
Main Authors Shiohara, Tetsuo, Mizukawa, Yoshiko, Shimoda-Komatsu, Yurie, Aoyama, Yumi
Format Journal Article
LanguageEnglish
Japanese
Published England Elsevier B.V 01.10.2018
JAPANESE SOCIETY OF ALLERGOLOGY
Elsevier
Subjects
Atopic dermatitis
Basal sweating
Impression mold technique
Inducible sweating
Leakage of sweat
FLG
TEWL
Leakage of sweat
AD
DCD
SSH
Basal sweating
Impression mold technique
SC
IMT
HZ
VZV
Atopic dermatitis
TJ
Inducible sweating
Online AccessGet full text

Cover

More Information
Summary:Although there is a growing acceptance that sweat could play a detrimental role in various allergic skin diseases, the possibility that sweat is also involved in maintenance of skin hydration and skin-specific immune responses has not been acknowledged. We initially describe physiological role of sweat in both maintaining skin hydration and thermoregulation. The purpose of this article is to provide the reader with objective evidence that sweating is intimately linked to vital stratum corneum barrier function and usefulness of application of moisturizers in clinical care of allergic skin diseases. This review also covers how sweating disturbance would leave the skin vulnerable to the development of various allergic skin diseases, such as atopic dermatitis. New therapeutic approaches would specifically target such sweating disturbance in these allergic skin diseases.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1323-8930
1440-1592
DOI:10.1016/j.alit.2018.07.010