Hepatic lymphangiomatosis in a young dog

"A 9-montn-old intact male American cocker spaniel was referred because or hepatomegaly and ascites. Ultrasonograpnic evaluation of the liver revealed congestion and increased parenchymal echogenicity with focal and more hyperechoic nodules. Histopathology of the hepatic lesion revealed diffuse...

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Published inJournal of Veterinary Medical Science Vol. 64; no. 8; pp. 743 - 745
Main Authors "Yamagami, T. (Marupi Lifetech Co. Ltd., Ikeda, Osaka (Japan)), Takemura, N, Washizu, T, Komori, S, Amasaki, H, Washizu, M.
Format Journal Article
LanguageEnglish
Published Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 01.08.2002
Japan Science and Technology Agency
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Summary:"A 9-montn-old intact male American cocker spaniel was referred because or hepatomegaly and ascites. Ultrasonograpnic evaluation of the liver revealed congestion and increased parenchymal echogenicity with focal and more hyperechoic nodules. Histopathology of the hepatic lesion revealed diffuse, ill-defined vascular proliferation. A single layer of endothelial cells, which showed signs of minimal cellular atypia, lined the irregular vessels. On immunohistochemistry, the proliferative endothelial cells lining the irregular vessels were positive for an antiserum to factor VIII related antigen. Based on these findings, the dog was diagnosed with hepatic lymphangiomatosis."
Bibliography:L70
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ISSN:0916-7250
1347-7439
DOI:10.1292/jvms.64.743