The tumor suppressor axis p53/miR-34a regulates Axl expression in B-cell chronic lymphocytic leukemia: implications for therapy in p53-defective CLL patients

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Bibliographic Details
Published inLeukemia Vol. 28; no. 2; pp. 451 - 455
Main Authors Boysen, J, Sinha, S, Price-Troska, T, Warner, S L, Bearss, D J, Viswanatha, D, Shanafelt, T D, Kay, N E, Ghosh, A K
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 01.02.2014
Nature Publishing Group
Subjects
3' Untranslated Regions
631/67/581
692/699/67/1059
692/699/67/1990/283/1895
Axl protein
Cancer Research
Care and treatment
Cell cycle
Chronic lymphocytic leukemia
Critical Care Medicine
Dendritic cells
Drug dosages
Drug withdrawal
Gene expression
Gene Expression Regulation, Leukemic
Genetic aspects
Hematology
Humans
Infections
Intensive
Internal Medicine
Kinases
letter-to-the-editor
Letters to the editor
Leukemia
Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy
Leukemia, Lymphocytic, Chronic, B-Cell - genetics
Leukemia, Lymphocytic, Chronic, B-Cell - metabolism
Lymphatic leukemia
Lymphocytes B
Medicine
Medicine & Public Health
MicroRNAs
MicroRNAs - genetics
MicroRNAs - metabolism
Molecular Targeted Therapy
Oncology
p53 Protein
Pathogens
Patients
Physiological aspects
Proto-Oncogene Proteins - genetics
Proto-Oncogene Proteins - metabolism
Receptor Protein-Tyrosine Kinases - genetics
Receptor Protein-Tyrosine Kinases - metabolism
RNA Interference
Tumor suppressor genes
Tumor Suppressor Protein p53 - genetics
Tumor Suppressor Protein p53 - metabolism
Tumors
West Nile virus
Italy
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These authors contributed equally
ISSN:0887-6924
1476-5551
DOI:10.1038/leu.2013.298