Paraganglioma of the urinary bladder first presented by bladder bloody tamponade: Two case reports and review of the literatures

• Published in: The Kaohsiung journal of medical sciences Vol. 27; no. 3; pp. 108 - 113
• Main Authors: Tsai, Chia-Chun, Wu, Wen-Jeng, Chueh, Kuang-Shun, Li, Wei-Ming, Huang, Chun-Hsiung, Wu, Chun-Chieh, Lee, Mei-Hui, Chen, Szu-Miao, 蔡嘉駿, 吳文正, 闕光瞬, 李威明, 黃俊雄, 吳俊杰, 李美慧, 陳思妙
• Format: Journal Article
• Language: English
• Published: China (Republic : 1949- ) Elsevier B.V 01.03.2011; John Wiley and Sons Inc; Wiley
• Subjects: Adult; Bloody tamponade; Case Report; Hematuria - complications; Humans; Internal Medicine; Male; Paraganglioma; Paraganglioma - complications; Paraganglioma - diagnosis; Urinary bladder; Urinary Bladder Neoplasms - complications; Urinary Bladder Neoplasms - diagnosis; 出血性填塞; 副節細胞瘤; 膀胱; Paraganglioma; 膀胱; Bloody tamponade; 出血性填塞; Urinary bladder; 副節細胞瘤
• ISSN: 1607-551X; 2410-8650; 2410-8650
• DOI: 10.1016/j.kjms.2010.05.005

Pheochromocytomas and paragangliomas (extra-adrenal pheochromocytomas) are catecholamine-secreting tumors. The paraganglioma of the urinary bladder is an uncommon neoplasm with a higher malignancy rate. Only about 60% of bladder paragangliomas presented with hematuria, and most of them were microscopic hematuria. Herein, we report two cases of bladder paraganglioma with bladder bloody tamponade. In Case 1, radical cystectomy and regional lymphadenectomy were performed for a huge bladder tumor and left pelvic lymph nodes metastasized. In Case 2, we chose endoscopic transurethral resection of the bladder tumor. Literatures since 1989 were also reviewed to illustrate the clinical characteristics and current treatments. 嗜鉻細胞瘤及非腎上腺之副節細胞瘤為兒茶酚胺分泌腫瘤。膀胱副節細胞瘤不但少見且有較高的惡性比率。根據統計，約只有60%的膀胱副節細胞瘤病人有血尿表現，而其中大多為肉眼不可見之血尿。在此提出兩位以嚴重出血性膀胱填塞為表現之膀胱副節細胞瘤病人。分別以根除性膀胱全切除與內視鏡經尿道膀胱腫瘤刮除手術作為治療方式。我們同時分析自1989年以來所有膀胱副節細胞瘤的病例系列報告，並回顧針對此特殊疾病的臨床診斷及治療方式。